Oslo Universitetssykehus Hf

Oslo

Anna Pasetto

Director of the Center for Advanced Cell Therapy (ACT)

Karl-Johan Malmberg

Unit leader

<p>Immunotherapy has become a cornerstone in cancer therapy that includes a broad array of strategies aiming to unleash, direct and boost the patients’ own immune- system through adoptive transfer of expanded naturally circulating or genetically engineered cytotoxic lymphocytes. Despite the recent clinical breakthroughs, the need for new therapies targeting resistant cases and other diseases, in particular solid tumors, remains high. To facilitate development of new therapies, Oslo University Hospital (OUH) has established a Center for Advanced Cell Therapy (ACT Center) within the section of Cell Therapy in cooperation with a private donor consortium.</p><p>Professor Malmbergs group in collaboration with the ACT Centre has a vacancy for a special engineer position to support the development of next generation NK-cell based therapy. The position is for 2 years with possibility of extension. We are looking for a highly motivated candidate with a strong interest in translational cell therapy research, including the development of preclinical and clinical protocols, and with excellent teamwork skills. The successful candidate will take part in the process development, automation and scaled manufacturing of a new NK cell product. Previous experience with work on NK or T cell expansion in pre-GMP and GMP settings is a merit.</p><p><em>Oslo University Hospital is a workplace with great diversity. We believe this is crucial for solving our tasks in the best possible way. We want this diversity to be reflected among the applicants for our positions, and we encourage all qualified candidates, regardless of background, to apply!</em></p><br />
<h3>Duties and responsibilities</h3><ul><li>Work in collaboration with the ACT-Center team to develop and optimize large scale production of NK cells for clinical trials</li><li>Evaluate and summarize data using analytical methodologies, interpreting results, drawing conclusions and recommending options for future experiments to achieve project goals.</li><li>Appropriately document experimental procedures and results according to established guidelines. For cGMP manufacturing, ensure documentation are filled out correctly, training is current and all quality requirements are being followed.</li><li>Participate in information requests from authorities and internal audits of the manufacturing </li></ul><h3>Qualifications</h3><ul><li>Applicants must as a minimum hold a MSc degree in medical technology, biological science, bioengineering, or related technical field.</li><li>Extensive experience with cell culturing, flow cytometry, molecular biology, and genetic engineering is required</li><li>Hands-on experience in a GMP environment is a merit</li><li>Excellent written and oral communication skills in English and a Scandinavian language.      </li></ul><h3>Personal qualities</h3><ul><li>Ability to work independently, but also be a great team player</li><li>Good communication skills</li><li>Ability to be flexible at work</li><li>Solution oriented          </li></ul><h3>We can offer</h3><ul><li>Opportunity to join a multi-disciplinary team at the international forefront to advance the development of new innovative cell therapies against cancer. </li><li>Opportunity to acquire competence in state-of-the-art technologies for GMP manufacturing of ATMP.</li><li>A stimulating scientific environment and a career in one of the most rapidly evolving fields of human medicine.    </li></ul><h3>Kontaktinformasjon</h3>Karl-Johan Malmberg, Unit leader, k.j.malmberg&#64;medisin.uio.no<br />
Anna Pasetto, Director of the Center for Advanced Cell Therapy (ACT), &#43;4740845745, annpas&#64;ous-hf.no<br />
<h3>Arbeidssted</h3>Ullernchausseen 70<br />
0379 Oslo<br />
<h3>Nøkkelinformasjon:</h3>Arbeidsgiver: Oslo universitetssykehus HF<br />
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Referansenr.: 4972524945<br />
Stillingsprosent: 100%<br />
Contract<br />
Startdato: 18.08.2025<br />
Søknadsfrist: 06.06.2025<br />
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Special Engineer