Norges Teknisk-naturvitenskapelige Universitet Ntnu

Trondheim

<h2>This is NTNU</h2><p>NTNU is a broad-based university with a technical-scientific profile and a focus in professional education. The university is located in three cities with headquarters in Trondheim.</p><p>At NTNU, 9,000 employees and 43,000 students work to create knowledge for a better world.</p><p>You will find more information about working at NTNU and the application process <a href="https://www.ntnu.edu/vacancies/" rel="nofollow">here.</a></p><p>   </p>. Video: https://youtu.be/Xt-yHCN5QS0<br /><h2>About the position</h2><p>There is a vacancy for one PhD candidate at The Department of Clinical and Molecular Medicine (Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU)). The PhD candidate will work on identifying novel functions of DNA repair enzymes in gene expression regulation, as part of ongoing research in <a href="https://www.ntnu.edu/employees/barbara.v.loon" rel="nofollow">the Van Loon group</a>.</p><p>Base excision repair (BER) is essential pathway for removal of aberrant DNA bases. We recently provided evidence that BER enzymes are in crosstalk with active transcription and impact gene expression. Building on these findings the project focuses on uncovering the mechanisms through which altered BER status regulates transcriptome composition, of relevance for unperturbed cellular physiology and overcoming diseases, such as cancer and brain diseases. To identify novel mechanisms through which BER factors regulate transcriptome, biochemical, single molecule microscopy, molecular and cell biology tools will be applied to cellular models of physiological developmental and diseases. </p><br /><h2>Required selection criteria</h2><ul><li>Practical experience in biochemistry/ chemistry/ biophysics and molecular biology/cell biology.</li><li>Your education must correspond to a five-year Norwegian degree programme, where 120 credits are obtained at master&#39;s level. </li><li>You must have a strong academic background in molecular or cell biology, biochemistry, chemistry or biophysics from your previous studies, and an average grade from the master&#39;s degree program, or equivalent education, which is equal to B or better compared with NTNU&#39;s grading scale. If you do not have letter grades from previous studies, you must have an equally good academic basis. If you have a weaker grade background, you may be assessed if you can document that you are particularly suitable for a PhD education. </li><li>You must meet the requirements for admission to the faculty&#39;s doctoral program (<a href="https://www.ntnu.edu/studies/phmedhv" rel="nofollow">PhD Programme in Medicine and Health Sciences - NTNU</a>). </li></ul><p><strong>PLEASE NOTE: For detailed information about what the application must contain, see paragraph “About the application”.</strong></p><p>If you cannot document skills in Norwegian, Swedish or Danish at <a href="https://prove.hkdir.no/en/language-levels" rel="nofollow">level A2</a> upon employment, you must complete <a href="https://www.ntnu.edu/norwegiancourse" rel="nofollow">Norwegian courses</a> corresponding to at least 15 credits before the end of the employment period. NTNU will facilitate this. </p><p>The appointment is to be made in accordance with <a href="https://lovdata.no/dokument/SF/forskrift/2024-06-28-1392/" rel="nofollow">Regulations for the Universities and Colleges Act (university and colleges regulations) and Regulations for the degrees philosophiae doctor (ph.d.) and philosophiae doctor (ph.d.) in artistic development work at the Norwegian University of Science and Technology (NTNU)</a> for general criteria for the position.</p><br /><h2>Preferred selection criteria</h2><ul><li>Excellent or very good diploma/master degree in biology or chemistry.</li><li>Good laboratory skills.</li><li>Good computer skills / data processing skills.</li><li>Good communications skills.</li><li>Good written and oral English language skills.</li><li>Experience in single molecule analysis, work with human cells, purified proteins, as well as basic skills in Python will be positively considered.</li></ul><br /><h2>Personal characteristics</h2><ul><li>Motivated, goal-oriented and well-organized.</li><li>A strong interest in DNA biology, especially genome regulation.</li><li>Ability to work in teams.</li><li>Ability to work independently.</li></ul><br /><h2>We offer</h2><ul><li>exciting and stimulating tasks in a strong international academic environment;</li><li>an open and inclusive work environment with dedicated colleagues;</li><li>state-of-the-art training opportunities;</li><li>favourable terms in the <a href="https://www.spk.no/en/membership-in-spk/" rel="nofollow">Norwegian Public Service Pension Fund (SPK)</a></li><li><a href="https://i.ntnu.no/wiki/-/wiki/English/Benefits&#43;and&#43;discounts" rel="nofollow">employee benefits and discounts</a>. </li></ul><br /><h2>Salary and conditions</h2><p>In the position of PhD Candidate, code 1017, your gross salary will normally be NOK  536 200,-  per annum depending on qualifications and seniority. A 2% statutory contribution to the State Pension Fund is deducted from the salary. </p><p>The employment period is 3 years. </p><p>For employment as a PhD Candidate, it is a prerequisite that you apply for admission to the <a href="https://www.ntnu.edu/studies/phmedhv" rel="nofollow">PhD Programme in Medicine and Health Sciences </a> within three months of your employment contract start date, and that you participate in an organized doctoral programme throughout the period of employment.</p><p>The appointment is carried out in accordance with the principles of the <a href="https://lovdata.no/dokument/NL/lov/2017-06-16-67" rel="nofollow">State Employees Act</a>, and <a href="https://www.regjeringen.no/en/topics/foreign-affairs/export-control/id754301/" rel="nofollow">Export control</a> (legislation that regulates the export of knowledge, technology and services). Candidates who, after assessment of the application and attachments, are considered to be in conflict with the criteria in the latter act, will not be able to be employed.</p><p>It is a prerequisite that you can be present at and accessible to the institution daily.</p><br /><h2>About the application</h2><p>The attachments  must accompany the application as these documents form the basis of the application assessment. The documents must be in  English. </p><p><strong>Please note:</strong> the application will only be assessed on the basis of the information we have received by the application deadline. Therefore, make sure that your application clearly shows how your skills and experience meet the criteria described above. The application and all attachments must be sent electronically via Jobbnorge.no. </p><p> The application must include: </p><ul><li>CV, motivation letter, certificates and diplomas. </li><li>transcripts and diplomas for bachelor&#39;s and master&#39;s degrees. If you have not completed the master&#39;s degree, you must submit a confirmation that the master&#39;s thesis has been submitted. </li><li>A copy of the master&#39;s thesis. If you recently have submitted your master&#39;s thesis, you can attach a draft of the thesis. Documentation of a completed master&#39;s degree must be presented before taking up the position. </li><li>Name and address of two referees. </li><li>One page research plan describing how you would analyse effects of mutations on the activities of BER enzymes and how would you determine their impacts on gene expression.</li></ul><p>If all, or parts, of your education has been taken abroad, we also ask you to attach documentation of the scope and quality of your entire education, both Bachelor&#39;s and Master&#39;s education, in addition to other higher education. A description of the documentation required can also be found <a href="https://www.ntnu.no/stillinger/dokumentasjon-av-utenlandsk-utdanning" rel="nofollow">here</a>. If you already have a statement from <a href="https://hkdir.no/en" rel="nofollow">Norwegian Directorate for Higher Education and Skills (HK-dir)</a>, please attach this as well. Diploma Supplement is required to attach for European Master Diplomas outside Norway. Chinese applicants are required to provide confirmation of Master Diploma from China Credentials Verification (CHSI).</p><p>In the evaluation of which candidate is best qualified, emphasis will be placed on education, experience and personal and interpersonal qualities. Motivation, ambitions, and potential will also count in the assessment of the candidates. </p><p>NTNU recognizes a wide range of academic contributions and has committed itself to The San Francisco Declaration on Research Assessment and CoARA (responsible assessment of research and recognition of a greater breadth of academic contributions in accordance with NTNU&#39;s social mission).</p><br /><h2>General information</h2><p>A public list of applicants with name, age, job title and municipality of residence is prepared after the application deadline. If you wish to be exempt from entry on the public applicant list, this must be justified. Assessment will be made in accordance with <a href="https://lovdata.no/lov/2006-05-19-16/%C2%A725" rel="nofollow">current legislation</a>. You will be notified if the exemption is not granted.</p><p>If you have any questions about the position, please contact Professor Barbara van Loon, telephone &#43;47 73 59 84 23, email <a href="mailto:barbara.v.loon&#64;ntnu.no" rel="nofollow">barbara.v.loon&#64;ntnu.no</a>. If you have any questions about the recruitment process, please contact Vebjørn F. Andreassen, e-mail: vebjorn.andreassen&#64;ntnu.no</p><p>Please submit your application electronically via jobbnorge.no with your CV, motivation letter, diplomas and certificates. Applications submitted elsewhere will not be considered.</p><p><strong>Application deadline: 09.06.2025</strong></p><p>-----------------</p><p>For practical information about <a href="https://www.ntnu.edu/nirs" rel="nofollow">working at NTNU, please visit this webpage. </a></p><p><br />Diversity is a strength, and at NTNU we aim to be an employer that reflects the diversity in society and that makes use of the potential of the population&#39;s collective skills. If you think this position is relevant and interesting, we encourage you to apply, regardless of gender, functional ability and cultural background, or whether you have been out of work for a period of time.</p><p><br /><a href="https://www.trondheim.kommune.no/english/" rel="nofollow"><strong>The city of Trondheim</strong></a> is a modern European city with a rich cultural scene. <a href="https://workintrondheim.no/" rel="nofollow">Trondheim is the tech capital of Norway</a> with a population of 200,000. The Norwegian welfare state, including healthcare, schools, kindergartens and overall equality, is probably the best of its kind in the world. Professional subsidized day-care for children is easily available. Furthermore, Trondheim offers great opportunities for education (including international schools) and possibilities to enjoy nature, culture and family life and has low crime rates and clean air quality. </p><br />

PhD Candidate in Molecular mechanisms of DNA repair